Gocha Khelashvili, Ph.D.
Research & Accomplishments
- Study of modulation of radiotherapy x-ray beams by strong magnetic fields created by superconducting thick solenoid. Dose escalation caused by trapping of electrons by magnetic field may have some clinical application. Using Monte Carlo simulations we “apply” magnetic field to various patient cases for various cancers. Those patients have been treated in the past by conventional radiotherapy methods. We conduct extensive study if magnetic field can provide additional therapeutic gain (more tumor dose and less healthy tissue damage) compared to existing treatment plans.
- Application of X-ray optics to imaging problems using a new phase sensitive imaging modalities called Diffraction Enhanced Imaging (DEI) and Multiple Image Radiography (MIR). My interest in this project include development of self-consistent theoretical model of DEI and MIR image formation, precise calculation and measurement of dose deposited to biological systems during DEI/MIR image acquisition and developing data analysis methods. This work is been performed in collaboration with University of Saskatchewan / Canadian Light Source (Saskatoon, Canada), Image Processing Laboratories of Illinois Institute of Technology and Nesch LLC (Crown Point, IN).
“The Use of Radiochromic Film for Tomotheraphy IMRT Dosimetric Verification”, Julius V. Turian, Gocha Khelashvili, James Chu Medical Physics, v.34, 2497-2498 (2007).
“Device and Method for Producing a Spatially Uniformly Intense Source of X-rays”, Timothy Morrison, Ivan Nesch and Gocha Khelashvili United States Patent, US 7,280,636 (2007).
“Physical Model of Multiple-Image Radiography”, Gocha Khelashvili, Jovan Brankov, Dean Chapman, Yongyi Yang, Mark Anastasio, Zhong Zhong and Miles Wernick, Physics in Medicine and Biology v.51 221-236 (2006).
“Progress in Multiple-image Radiography” Miles Wernick, Jovan Brankov, Dean Chapman, Yongyi Yang, Gocha Khelashvili, Mark Anastasio, Zhong Zhong, Christopher Parham, Jun Li and Carol Muehleman, Computational Imaging IV, Vol. 6065, ISBN/ISSN: 0-8194-6105-9, pages 256-263 (2006).
“Physical Model of Image Formation in Multiple-Image Radiography”, Jovan Brankov, Gocha Khelashvili, Dean Chapman, Yongyi Yang, Mark Anastasio, Zhong, Zhong and Miles Wernick, IEEE Nuclear Science Symposium Conference, M07-362 (2005).
“New Methods of EXAFS Analysis in Structural Genomics”, Grant Bunker, Nicholas Dimakis and Gocha Khelashvili, Journal of Synchrotron Radiation, v.12, 53-56 (2005).
“A Novel Method of Bending Crystals to Log Spiral Shape”, Gocha Khelashvili, Ivan Nesch, Timothy I. Morrison, Grant Bunker and Dean Chapman, Review of Scientific Instruments, Vol. 73, No. 3, 1534 (2002).
“Practical Regularization Methods for Analysis of EXAFS Spectra”, Gocha Khelashvili and Grant Bunker, Journal of Synchrotron Radiation, 6, 271 (1999).
“Nonrenormalizability of the Massive Super-Yang-Mills Theory”, Gocha Khelashvili and Victor Ogievestky, Modern Physics Letters A, Vol. 6, No. 23, 2143 (1991).
“Theory of Massive N=2 Super-Yang-Mills Fields”, Gocha Khelashvili and Victor Ogievetsky, JINR-E2-91-217 (1991).