This course covers modern aspects of chemical analysis. It is designed to give the student a solid conceptual ground to understand how a given analytical technique works including its limits and advantages. The emphasis is on solutions analysis and the course is roughly divided into: (i) Basic measurements and concepts; (ii) spectroscopy; and (iii) chromatography and mass spectrometry. Upon completion of this course, the student will be able to: describe the basic setup and operation of separation, mass spectrometric, and spectroscopic instrumentation; interpret spectra from various instruments as a means for qualitative and quantitative analysis; apply basic knowledge of separation technique, mass spectrometry, and spectroscopy for practical problem solving; relate the use of separation technique, mass spectrometry, and spectroscopy to his or her own research interests; and compile, present, and explain modern techniques for analytical research. Topics includes high-performance liquid chromatography, gas chromatography, atomic spectrometry, molecular spectrometry, UV/vis spectroscopy, molecular luminescence, infrared spectrometry, mass spectrometry, radio chemistry, raman spectroscopy, nuclear magnetic resonance spectroscopy, etc.